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Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743355508

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

About this item

Full title

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2007-07, Vol.448 (7149), p.73-77

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neuronal rescue
The drugs currently available for Parkinson's disease patients generally treat only the symptoms, and do not prevent the degeneration and death of dopaminergic neurons in the brain, the cause the motor defects associated with the disease. Treatment with glial cell line-derived neurotrophic factor (GDNF) has had limited success, b...

Alternative Titles

Full title

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743355508

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743355508

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature05957

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