Regulated Cleavage of a Contact-Mediated Axon Repellent
Regulated Cleavage of a Contact-Mediated Axon Repellent
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Publisher
Washington, DC: American Society for the Advancement of Science
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Language
English
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Washington, DC: American Society for the Advancement of Science
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Scope and Contents
Contents
Contact-mediated axon repulsion by ephrins raises an unresolved question: these cell surface ligands form a high-affinity multivalent complex with their receptors present on axons, yet rather than being bound, axons can be rapidly repelled. We show here that ephrin-A2 forms a stable complex with the metalloprotease Kuzbanian, involving interactions...
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Full title
Regulated Cleavage of a Contact-Mediated Axon Repellent
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Record Identifier
TN_cdi_proquest_miscellaneous_743412769
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743412769
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.289.5483.1360
