Regulation of CD8⁺ T Cell Development by Thymus-Specific Proteasomes
Regulation of CD8⁺ T Cell Development by Thymus-Specific Proteasomes
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Proteasomes are responsible for generating peptides presented by the class I major histocompatibility complex (MHC) molecules of the immune system. Here, we report the identification of a previously unrecognized catalytic subunit called β5t. β5t is expressed exclusively in cortical thymic epithelial cells, which are responsible for the positive sel...
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Full title
Regulation of CD8⁺ T Cell Development by Thymus-Specific Proteasomes
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TN_cdi_proquest_miscellaneous_743413143
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743413143
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1141915
