Log in to save to my catalogue

Real-Time DNA Sequencing from Single Polymerase Molecules

Real-Time DNA Sequencing from Single Polymerase Molecules

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743418664

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

We present single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescently labeled deoxyribonucleoside triphosphates (dNTPs). We detected the temporal order of their enzymatic incorporation into a growing DNA strand with zero-mode waveguide nanos...

Alternative Titles

Full title

Real-Time DNA Sequencing from Single Polymerase Molecules

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743418664

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743418664

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1162986

How to access this item