ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Cellular responses to DNA damage are mediated by a number of protein kinases, including ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3-related). The outlines of the signal transduction portion of this pathway are known, but little is known about the physiological scope of the DNA damage response (DDR). We performed a large-scale proteomi...
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ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
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TN_cdi_proquest_miscellaneous_743529956
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743529956
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1140321
