Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis
Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis
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Washington, DC: American Society for the Advancement of Science
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Language
English
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Washington, DC: American Society for the Advancement of Science
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Contents
The proapoptotic Bax protein induces cell death by acting on mitochondria. Bax binds to the permeability transition pore complex (PTPC), a composite proteaceous channel that is involved in the regulation of mitochondrial membrane permeability. Immunodepletion of Bax from PTPC or purification of PTPC from Bax-deficient mice yielded a PTPC that could...
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Full title
Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis
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TN_cdi_proquest_miscellaneous_743649156
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743649156
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.281.5385.2027
