Inactivation of Misselected CD8 T Cells by CD8 Gene Methylation and Cell Death
Inactivation of Misselected CD8 T Cells by CD8 Gene Methylation and Cell Death
About this item
Full title
Author / Creator
Publisher
Washington, DC: American Society for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Society for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Misselected CD8 cells that express T cell receptors (TCRs) that do not recognize class 1 major histocompatibility complex (MHC) protein can emerge from thymic selection. A postthymic quality control mechanism that purges these cells from the repertoire is defined here. The failure of mature CD8 cells to simultaneously engage their TCR and CD8 corec...
Alternative Titles
Full title
Inactivation of Misselected CD8 T Cells by CD8 Gene Methylation and Cell Death
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_743704295
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743704295
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.284.5417.1187
