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Inhibition of invasion of epithelial cells by Tiam(1)-Rac signaling

Inhibition of invasion of epithelial cells by Tiam(1)-Rac signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743709803

Inhibition of invasion of epithelial cells by Tiam(1)-Rac signaling

About this item

Full title

Inhibition of invasion of epithelial cells by Tiam(1)-Rac signaling

Publisher

Washington: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1997-11, Vol.278 (5342), p.1464-1466

Language

English

Formats

Publication information

Publisher

Washington: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Tiam1 encodes an exchange factor for the Rho-like guanosine triphosphatase Rac. Both Tiam1 and activated RacV12 promote invasiveness of T lymphoma cells. In epithelial Madin-Darby canine kidney (MDCK) cells, Tiam1 localized to adherens junctions. Ectopic expression of Tiam1 or RacV12 inhibited hepatocyte growth factor-induced scattering by increasi...

Alternative Titles

Full title

Inhibition of invasion of epithelial cells by Tiam(1)-Rac signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743709803

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743709803

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

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