An Anti-Apoptotic Role for the p53 Family Member, p73, during Developmental Neuron Death
An Anti-Apoptotic Role for the p53 Family Member, p73, during Developmental Neuron Death
About this item
Full title
Author / Creator
Publisher
Washington, DC: American Society for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Society for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
p53 plays an essential pro-apoptotic role, a function thought to be shared with its family members p73 and p63. Here, we show that p73 is primarily present in developing neurons as a truncated isoform whose levels are dramatically decreased when sympathetic neurons apoptose after nerve growth factor (NGF) withdrawal. Increased expression of truncat...
Alternative Titles
Full title
An Anti-Apoptotic Role for the p53 Family Member, p73, during Developmental Neuron Death
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_743710359
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743710359
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.289.5477.304
