Organogenic Role of B Lymphocytes in Mucosal Immunity
Organogenic Role of B Lymphocytes in Mucosal Immunity
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Washington, DC: American Society for the Advancement of Science
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Language
English
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Washington, DC: American Society for the Advancement of Science
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Contents
Follicle-associated epithelium (FAE) in the intestinal Peyer's patches contains M cells that deliver pathogens to organized lymphoid tissue. Development of Peyer's patches, FAE, and M cells was found to be impaired in mice that had no B cells. Transgenic expression of membrane-bound immunoglobulin M restored B cells and FAE development. The lack of...
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Full title
Organogenic Role of B Lymphocytes in Mucosal Immunity
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TN_cdi_proquest_miscellaneous_743738288
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743738288
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.286.5446.1965
