Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact...
Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact similar to male gender or smoking in schizophrenic patients
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Purpose The impact of the UGT1A4, CYP1A2, and MDR1 genetic variants on olanzapine plasma levels, in relation to those of other individual factors, such as gender, smoking status, body weight, and age, was investigated in patients with schizophrenia. Methods A total of 121 patients were recruited from psychosis-specialized outpatient departments in...
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Full title
Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact similar to male gender or smoking in schizophrenic patients
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TN_cdi_proquest_miscellaneous_744592498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744592498
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ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-009-0783-8
