Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD
Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD
About this item
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Author / Creator
Ogawa, Y , Dogru, M , Uchino, M , Tatematsu, Y , Kamoi, M , Yamamoto, Y , Ogawa, J , Ishida, R , Kaido, M , Hara, S , Matsumoto, Y , Kawakita, T , Okamoto, S and Tsubota, K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
Fibrosis and excessive extracellular matrix production are characteristic features of lacrimal gland chronic GVHD (cGVHD). Tranilast (n-[3,4-anthoranilic acid]), used for fibrotic skin disease, inhibits transforming growth factor-β-induced matrix production. We conducted a non-randomized study comparing 8 patients (five men, three women; median age...
Alternative Titles
Full title
Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_744625572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744625572
Other Identifiers
ISSN
0268-3369
E-ISSN
1476-5365
DOI
10.1038/bmt.2009.173
