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Recombinant Glucocerebrosidase (Imiglucerase) as a Therapy for Gaucher Disease

Recombinant Glucocerebrosidase (Imiglucerase) as a Therapy for Gaucher Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744682612

Recombinant Glucocerebrosidase (Imiglucerase) as a Therapy for Gaucher Disease

About this item

Full title

Recombinant Glucocerebrosidase (Imiglucerase) as a Therapy for Gaucher Disease

Author / Creator

Publisher

Cham: Springer International Publishing

Journal title

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2010-02, Vol.24 (1), p.41-47

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Imiglucerase is a recombinant formulation of human glucocerebrosidase, which is administered to patients with Gaucher disease (GD) as enzyme replacement therapy (ERT). Imiglucerase is generated from transduced Chinese hamster ovary cells, and modified by sequential deglycosylation of its carbohydrate side chains to expose α-mannosyl residues that m...

Alternative Titles

Full title

Recombinant Glucocerebrosidase (Imiglucerase) as a Therapy for Gaucher Disease

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_744682612

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744682612

Other Identifiers

ISSN

1173-8804

E-ISSN

1179-190X

DOI

10.2165/11318540-000000000-00000

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