Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction...
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
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Author / Creator
Ehses, J. A , Meier, D. T , Wueest, S , Rytka, J , Boller, S , Wielinga, P. Y , Schraenen, A , Lemaire, K , Debray, S , Van Lommel, L , Pospisilik, J. A , Tschopp, O , Schultze, S. M , Malipiero, U , Esterbauer, H , Ellingsgaard, H , Rütti, S , Schuit, F. C , Lutz, T. A , Böni-Schnetzler, M , Konrad, D and Donath, Marc Y
Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
Aims/hypothesis Inflammation contributes to both insulin resistance and pancreatic beta cell failure in human type 2 diabetes. Toll-like receptors (TLRs) are highly conserved pattern recognition receptors that coordinate the innate inflammatory response to numerous substances, including NEFAs. Here we investigated a potential contribution of TLR2 t...
Alternative Titles
Full title
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
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Record Identifier
TN_cdi_proquest_miscellaneous_744707932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744707932
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-010-1747-3
