Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxi...
Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
SUPERANTIGENS stimulate T cells bearing particular T-cell receptor
Vβ
sequences
1,2
, so they are extremely potent polyclonal T-cell mitogens. T-cell activation is preceded by binding of superantigens to class II major histocompatibility complex (MHC) molecules
3
. To further the structural characterization of these interactions,...
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Full title
Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1
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TN_cdi_proquest_miscellaneous_745657930
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745657930
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/367094a0
