Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell l...
Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein
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Author / Creator
Li, Guo-Hui , Fan, Yu-Zhen , Liu, Xiao-Wei , Zhang, Bing-Fang , Yin, Dan-Dan , He, Fei , Huang, Si-Yong , Kang, Zhi-Jie , Xu, Heng , Liu, Qiang , Wu, Yan-Lan , Niu, Xiao-Li , Zhang, Li , Liu, Li , Hao, Miao-Wang , Han, Hua and Liang, Ying-Min
Publisher
Boston: Boston : Springer US
Journal title
Language
English
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Publisher
Boston: Boston : Springer US
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Scope and Contents
Contents
The Notch signaling pathway has been implicated in the development of several leukemia and lymphoma. In order to investigate the relationship between Notch signaling and acute myeloid leukemia (AML), in this study, we expressed a recombinant Notch ligand protein, the DSL domain of the human Jagged1 fused with GST (GST-Jag1). GST-Jag1 could activate...
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Full title
Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein
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Record Identifier
TN_cdi_proquest_miscellaneous_745713756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745713756
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ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-010-0394-9
