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Evasion of CD8⁺ T Cells Is Critical for Superinfection by Cytomegalovirus

Evasion of CD8⁺ T Cells Is Critical for Superinfection by Cytomegalovirus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745929989

Evasion of CD8⁺ T Cells Is Critical for Superinfection by Cytomegalovirus

About this item

Full title

Evasion of CD8⁺ T Cells Is Critical for Superinfection by Cytomegalovirus

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2010-04, Vol.328 (5974), p.102-106

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Cytomegalovirus (CMV) can superinfect persistently infected hosts despite CMV-specific humoral and cellular immunity; however, how it does so remains undefined. We have demonstrated that superinfection of rhesus CMV-infected rhesus macaques (RM) requires evasion of CD8⁺ T cell immunity by virally encoded inhibitors of major histocompatibility compl...

Alternative Titles

Full title

Evasion of CD8⁺ T Cells Is Critical for Superinfection by Cytomegalovirus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_745929989

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745929989

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1185350

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