Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction
Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Robust type-I interferon (IFN-α/β) induction in plasmacytoid dendritic cells, through the activation of Toll-like receptor 9 (TLR9), constitutes a critical aspect of immunity
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. It is absolutely dependent on the transcription factor IRF-7, which interacts with and is activated by the adaptor...
Alternative Titles
Full title
Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction
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Record Identifier
TN_cdi_proquest_miscellaneous_746081162
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746081162
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature03547
