Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II
Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II
About this item
Full title
Author / Creator
Schneider, Tanja , Kruse, Thomas , Wimmer, Reinhard , Wiedemann, Imke , Sass, Vera , Pag, Ulrike , Jansen, Andrea , Nielsen, Allan K , Mygind, Per H , Raventós, Dorotea S , Neve, Søren , Ravn, Birthe , Bonvin, Alexandre M.J.J , De Maria, Leonardo , Andersen, Anders S , Gammelgaard, Lora K , Sahl, Hans-Georg and Kristensen, Hans-Henrik
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Host defense peptides such as defensins are components of innate immunity and have retained antibiotic activity throughout evolution. Their activity is thought to be due to amphipathic structures, which enable binding and disruption of microbial cytoplasmic membranes. Contrary to this, we show that plectasin, a fungal defensin, acts by directly bin...
Alternative Titles
Full title
Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II
Authors, Artists and Contributors
Author / Creator
Kruse, Thomas
Wimmer, Reinhard
Wiedemann, Imke
Sass, Vera
Pag, Ulrike
Jansen, Andrea
Nielsen, Allan K
Mygind, Per H
Raventós, Dorotea S
Neve, Søren
Ravn, Birthe
Bonvin, Alexandre M.J.J
De Maria, Leonardo
Andersen, Anders S
Gammelgaard, Lora K
Sahl, Hans-Georg
Kristensen, Hans-Henrik
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_746082573
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746082573
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1185723
