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Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with...

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746227328

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis

About this item

Full title

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Cancer chemotherapy and pharmacology, 2010-07, Vol.66 (2), p.357-371

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

Purpose In this pharmacokinetic/pharmacodynamic meta-analysis, we investigated relationships between clinical endpoints and sunitinib exposure in patients with advanced solid tumors, including patients with gastrointestinal stromal tumor (GIST) and metastatic renal cell carcinoma (mRCC). Methods Pharmacodynamic data were available for 639 patients...

Alternative Titles

Full title

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_746227328

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746227328

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-009-1170-y

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