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mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746231849

mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

About this item

Full title

mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (11), p.4925-4930

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair pathway. Three DNA glycosylases have been identified in mammals that are homologous to the Escherichia coli Fpg and Nei proteins, Neil1, Neil2, and Neil3. Neil1 and Neil2 in huma...

Alternative Titles

Full title

mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_746231849

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746231849

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0908307107

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