mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo
mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair pathway. Three DNA glycosylases have been identified in mammals that are homologous to the Escherichia coli Fpg and Nei proteins, Neil1, Neil2, and Neil3. Neil1 and Neil2 in huma...
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Full title
mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo
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TN_cdi_proquest_miscellaneous_746231849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746231849
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0908307107