Ca sub()V.2 b-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations
Ca sub()V.2 b-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations
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Full title
Ca sub()V.2 b-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations
Author / Creator
Journal title
Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (11), p.4996-5000
Language
English
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Scope and Contents
Contents
Excessive activation of calmodulin kinase II (CaMKII) causes arrhythmias and heart failure, but the cellular mechanisms for CaMKII-targeted proteins causing disordered cell membrane excitability and myocardial dysfunction remain uncertain. Failing human cardiomyocytes exhibit increased CaMKII and voltage-gated Ca super(2+) channel (Ca sub()V.2) act...
Alternative Titles
Full title
Ca sub()V.2 b-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_746231867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746231867
Other Identifiers
ISSN
0027-8424
DOI
10.1073/pnas.0913760107
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