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An analysis of genetic variation across the MBL2 locus in dutch Caucasians indicates that 3' haploty...

An analysis of genetic variation across the MBL2 locus in dutch Caucasians indicates that 3' haploty...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746278476

An analysis of genetic variation across the MBL2 locus in dutch Caucasians indicates that 3' haplotypes could modify circulating levels of mannose-binding lectin

About this item

Full title

An analysis of genetic variation across the MBL2 locus in dutch Caucasians indicates that 3' haplotypes could modify circulating levels of mannose-binding lectin

Publisher

Heidelberg: Springer

Journal title

Human genetics, 2005-12, Vol.118 (3-4), p.404-415

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer

More information

Scope and Contents

Contents

Mannose-binding protein (MBL) is a critical component of innate immunity and provides first-line protection against pathogens. Both circulating MBL serum levels and functional activity have been correlated with common genetic variants in the MBL2 gene. Associations between MBL deficiency and severe infections have been reported in immuno-incompeten...

Alternative Titles

Full title

An analysis of genetic variation across the MBL2 locus in dutch Caucasians indicates that 3' haplotypes could modify circulating levels of mannose-binding lectin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_746278476

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746278476

Other Identifiers

ISSN

0340-6717

E-ISSN

1432-1203

DOI

10.1007/s00439-005-0053-5

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