Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis
Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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The programmed death-1 (PD-1) costimulatory receptor inhibits T and B cell responses and plays a crucial role in peripheral tolerance. PD-1 has recently been shown to inhibit T cell responses during chronic viral infections such as HIV. In this study, we examined the role of PD-1 in infection with Mycobacterium tuberculosis, a common co-infection w...
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Full title
Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis
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TN_cdi_proquest_miscellaneous_748932483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748932483
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1007394107
