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Reduced Aquaporin3 Expression and Survival of Keratinocytes in the Depigmented Epidermis of Vitiligo

Reduced Aquaporin3 Expression and Survival of Keratinocytes in the Depigmented Epidermis of Vitiligo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748952539

Reduced Aquaporin3 Expression and Survival of Keratinocytes in the Depigmented Epidermis of Vitiligo

About this item

Full title

Reduced Aquaporin3 Expression and Survival of Keratinocytes in the Depigmented Epidermis of Vitiligo

Author / Creator

Publisher

New York, NY: Elsevier Inc

Journal title

Journal of investigative dermatology, 2010-09, Vol.130 (9), p.2231-2239

Language

English

Formats

Publication information

Publisher

New York, NY: Elsevier Inc

More information

Scope and Contents

Contents

Activation of the phosphatidylinositol 3-kinase (PI3K)/AKT pathway is critical for the survival of differentiating cells and depends on the E-cadherin–catenin complex. In an earlier study we showed impaired PI3K/AKT activation in vitiliginous keratinocytes (KCs). Recently, aquaporin3 (AQP3) has been reported to co-accumulate with E-cadherin in form...

Alternative Titles

Full title

Reduced Aquaporin3 Expression and Survival of Keratinocytes in the Depigmented Epidermis of Vitiligo

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_748952539

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748952539

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2010.99

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