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Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery

Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748956635

Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery

About this item

Full title

Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery

Publisher

New York, NY: Mosby, Inc

Journal title

The American heart journal, 2010-08, Vol.160 (2), p.362-369

Language

English

Formats

Publication information

Publisher

New York, NY: Mosby, Inc

More information

Scope and Contents

Contents

Background Heparin-induced thrombocytopenia (HIT) is caused by anti–platelet factor 4/heparin (PF4/H) immunoglobulin (Ig) G antibodies, which activate platelets. In some patients, anti-PF4/H antibodies are already detectable before cardiac surgery. Whether preoperative presence of antibodies confers adverse prognosis and which particular antibody c...

Alternative Titles

Full title

Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_748956635

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748956635

Other Identifiers

ISSN

0002-8703

E-ISSN

1097-6744

DOI

10.1016/j.ahj.2010.05.026

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