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The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1...

The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748979061

The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines

About this item

Full title

The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2010-08, Vol.90 (8), p.1259-1269

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Melanoma, the most deadly form of skin cancer, is aggressive and resistant to current therapies. It has been previously reported that the substance P and neurokinin-1 (NK-1) receptor antagonists induce cell proliferation and cell inhibition, respectively, in human melanoma cell lines. Aprepitant is a selective high-affinity antagonist of the human...

Alternative Titles

Full title

The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_748979061

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_748979061

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.2010.92

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