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Dual roles of PGE sub(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

Dual roles of PGE sub(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754538932

Dual roles of PGE sub(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

About this item

Full title

Dual roles of PGE sub(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (27), p.12233-12238

Language

English

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Scope and Contents

Contents

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). Although prostaglandin (PG) concentrations are increased in cerebrospinal fluid of MS patients, the role of PGs in MS is unknown. We examined this issue by subjecting mice deficient in each PG receptor type or subtype to EAE induction and using agonists o...

Alternative Titles

Full title

Dual roles of PGE sub(2)-EP4 signaling in mouse experimental autoimmune encephalomyelitis

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_754538932

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754538932

Other Identifiers

ISSN

0027-8424

DOI

10.1073/pnas.0915112107

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