Association of Mannose-Binding Lectin Deficiency with Acute Invasive Aspergillosis in Immunocompromi...
Association of Mannose-Binding Lectin Deficiency with Acute Invasive Aspergillosis in Immunocompromised Patients
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Oxford: The University of Chicago Press
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Language
English
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Publisher
Oxford: The University of Chicago Press
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Background. Invasive aspergillosis is a devastating infection with attributable mortality of 40% despite antifungal therapy. In animal models of aspergillosis, deficiency of mannose-binding lectin (MBL), a pattern recognition receptor that activates complement, is a susceptibility factor. MBL deficiency occurs in 20%-30% of the population. We hypot...
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Full title
Association of Mannose-Binding Lectin Deficiency with Acute Invasive Aspergillosis in Immunocompromised Patients
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TN_cdi_proquest_miscellaneous_754540177
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754540177
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ISSN
1058-4838
E-ISSN
1537-6591
DOI
10.1086/644619
