Spliceosome discards intermediates via the DEAH box ATPase Prp43p
Spliceosome discards intermediates via the DEAH box ATPase Prp43p
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
To promote fidelity in nuclear pre-mRNA splicing, the spliceosome rejects and discards suboptimal substrates that have engaged the spliceosome. Whereas DExD/H box ATPases have been implicated in rejecting suboptimal substrates, the mechanism for discarding suboptimal substrates has remained obscure. Corroborating evidence that suboptimal, mutated l...
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Full title
Spliceosome discards intermediates via the DEAH box ATPase Prp43p
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TN_cdi_proquest_miscellaneous_754876298
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754876298
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906022107