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Spliceosome discards intermediates via the DEAH box ATPase Prp43p

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754876298

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

About this item

Full title

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (22), p.10020-10025

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

To promote fidelity in nuclear pre-mRNA splicing, the spliceosome rejects and discards suboptimal substrates that have engaged the spliceosome. Whereas DExD/H box ATPases have been implicated in rejecting suboptimal substrates, the mechanism for discarding suboptimal substrates has remained obscure. Corroborating evidence that suboptimal, mutated l...

Alternative Titles

Full title

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_754876298

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754876298

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0906022107

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