Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
About this item
Full title
Author / Creator
Massberg, Steffen , Grahl, Lenka , von Bruehl, Marie-Luise , Manukyan, Davit , Pfeiler, Susanne , Goosmann, Christian , Brinkmann, Volker , Lorenz, Michael , Bidzhekov, Kiril , Khandagale, Avinash B , Konrad, Ildiko , Kennerknecht, Elisabeth , Reges, Katja , Holdenrieder, Stefan , Braun, Siegmund , Reinhardt, Christoph , Spannagl, Michael , Preissner, Klaus T and Engelmann, Bernd
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Neutrophils release the serine proteases neutrophil elastase and cathepsin G, which have microbicidal activity and thereby contribute to the innate immune response. Steffen Massberg
et al
. now show that these neutrophil serine proteases, in association with extracellular nucleosomes, can also promote coagulation and thrombosis within large b...
Alternative Titles
Full title
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
Authors, Artists and Contributors
Author / Creator
Grahl, Lenka
von Bruehl, Marie-Luise
Manukyan, Davit
Pfeiler, Susanne
Goosmann, Christian
Brinkmann, Volker
Lorenz, Michael
Bidzhekov, Kiril
Khandagale, Avinash B
Konrad, Ildiko
Kennerknecht, Elisabeth
Reges, Katja
Holdenrieder, Stefan
Braun, Siegmund
Reinhardt, Christoph
Spannagl, Michael
Preissner, Klaus T
Engelmann, Bernd
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_754885833
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754885833
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2184
