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Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous ke...

Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous ke...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_756308532

Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes

About this item

Full title

Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes

Publisher

Boston: Springer US

Journal title

Apoptosis (London), 2010-10, Vol.15 (10), p.1234-1246

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Teriflunomide (TFN) reportedly inhibits de novo pyrimidine synthesis and exhibits anti-inflammatory, disease-modifying activities in vivo. These qualities would suggest that TFN could be useful in skin cancer chemoprevention or therapy. We investigated some mechanistic aspects of this tenet by characterizing the effects of TFN on premalignant and m...

Alternative Titles

Full title

Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_756308532

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_756308532

Other Identifiers

ISSN

1360-8185

E-ISSN

1573-675X

DOI

10.1007/s10495-010-0518-4

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