Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter
Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter
About this item
Full title
Author / Creator
Publisher
United States: American Society for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Major histocompatibility complex (MHC) class I molecules present peptides derived from nuclear and cytosolic proteins to CD8$^+$ T cells. These peptides are translocated into the lumen of the endoplasmic reticulum (ER) to associate with class I molecules. Two MHC-encoded putative transporter proteins, TAP1 and TAP2, are required for efficient assem...
Alternative Titles
Full title
Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_75868008
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_75868008
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.8342042
