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CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-in...

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_759319304

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

About this item

Full title

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2007-12, Vol.8 (12), p.1324-1336

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Although host defense against human immunodeficiency virus 1 (HIV-1) relies mainly on cell-mediated immunity (CMI), the determinants of CMI in humans are poorly understood. Here we demonstrate that variations in the genes encoding the chemokine CCL3L1 and HIV coreceptor CCR5 influence CMI in both healthy and HIV-infected individuals.
CCL3L1
-...

Alternative Titles

Full title

CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_759319304

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_759319304

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni1521

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