The DNA repair protein Rad23 is a negative regulator of multi-ubiquitin chain assembly
The DNA repair protein Rad23 is a negative regulator of multi-ubiquitin chain assembly
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Rad23 is a nucleotide-excision repair protein with a previously unknown biochemical function. We determined that yeast and human Rad23 inhibited multi-ubiquitin (Ub) chain formation and the degradation of proteolytic substrates. Significantly, Rad23 could be co-precipitated with a substrate that contained a short multi-Ub chain. The UV sensitivity...
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The DNA repair protein Rad23 is a negative regulator of multi-ubiquitin chain assembly
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TN_cdi_proquest_miscellaneous_762278925
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762278925
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/35023547
