Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
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Full title
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The expression of the insulin-like growth factor 2 (
Igf2
) and
H19
genes is imprinted. Although these neighbouring genes share an enhancer
1
,
H19
is expressed only from the maternal allele, and
Igf2
only from the paternally inherited allele
2
,
3
. A region of paternal-specific methylation upstream of
...
Alternative Titles
Full title
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
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TN_cdi_proquest_miscellaneous_762279683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762279683
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/35013100
