Log in to save to my catalogue

The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76242613

The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

About this item

Full title

The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1985-08, Vol.229 (4715), p.767-769

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

The human c-mos proto-oncogene is located on chromosome 8 at band q22, close to the breakpoint in the t(8;21) (q22;q22) chromosome rearrangement. This translocation is associated with acute myeloblastic leukemia, subgroup M2. The c-myc gene, another proto-oncogene, has been mapped to 8q24. The breakpoint at 8q22 separates these genes, as determined...

Alternative Titles

Full title

The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_76242613

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76242613

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.3860954

How to access this item