The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia
The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia
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United States: The American Association for the Advancement of Science
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English
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United States: The American Association for the Advancement of Science
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Contents
The human c-mos proto-oncogene is located on chromosome 8 at band q22, close to the breakpoint in the t(8;21) (q22;q22) chromosome rearrangement. This translocation is associated with acute myeloblastic leukemia, subgroup M2. The c-myc gene, another proto-oncogene, has been mapped to 8q24. The breakpoint at 8q22 separates these genes, as determined...
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The Role of the c-mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia
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TN_cdi_proquest_miscellaneous_76242613
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76242613
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.3860954