Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment
Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment
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Publisher
Waltham, MA: Massachusetts Medical Society
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Language
English
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Publisher
Waltham, MA: Massachusetts Medical Society
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Scope and Contents
Contents
Clopidogrel must be metabolized to an active form to be effective. Cytochrome P-450 variants resulting in slow metabolism may reduce clinical efficacy. This study in patients with acute coronary syndromes or atrial fibrillation did not confirm diminished efficacy in those with slow metabolism.
Clopidogrel, when added to aspirin, reduces the rate...
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Full title
Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment
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TN_cdi_proquest_miscellaneous_762685914
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762685914
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1008410
