ZAP-70 Deficiency in an Autosomal Recessive Form of Severe Combined Immunodeficiency
ZAP-70 Deficiency in an Autosomal Recessive Form of Severe Combined Immunodeficiency
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Publisher
Washington, DC: American Society for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Contents
Protein tyrosine kinases (PTKs) play an integral role in T cell activation and differentiation. Defects in the Src-family PTKs in mice and in T cell lines have resulted in variable defects in thymic development and in T cell antigen receptor (TCR) signal transduction. Here, three siblings are described with an autosomal recessive form of severe com...
Alternative Titles
Full title
ZAP-70 Deficiency in an Autosomal Recessive Form of Severe Combined Immunodeficiency
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TN_cdi_proquest_miscellaneous_76525988
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76525988
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.8202713
