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Induction of the c-fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

Induction of the c-fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76928862

Induction of the c-fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

About this item

Full title

Induction of the c-fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

Publisher

Washington, DC: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1986-07, Vol.233 (4762), p.458-460

Language

English

Formats

Publication information

Publisher

Washington, DC: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Rat thyroid cells in culture, rendered quiescent by hormone deprivation, can be stimulated to undergo DNA synthesis in the absence of serum by the addition of purified thyrotropin. The primary effect in response to thyrotropin action in thyroid cells is the induction of the c-fos oncogene, followed by c-myc expression. This suggests that thyrotropi...

Alternative Titles

Full title

Induction of the c-fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_76928862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76928862

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.3726540

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