Cutaneous Transfection and Immune Responses to Intradermal Nucleic Acid Vaccination Are Significantl...
Cutaneous Transfection and Immune Responses to Intradermal Nucleic Acid Vaccination Are Significantly Enhanced by in Vivo Electropermeabilization
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United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Naked DNA injection with electropermeabilization (EP) is a promising method for nucleic acid vaccination (NAV) and in vivo gene therapy. Skin is an ideal target for NAV due to ease of administration and the accessibility of large numbers of antigen-presenting cells within the tissue. This study demonstrates that in vivo skin EP may be used to incre...
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Full title
Cutaneous Transfection and Immune Responses to Intradermal Nucleic Acid Vaccination Are Significantly Enhanced by in Vivo Electropermeabilization
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TN_cdi_proquest_miscellaneous_76956506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76956506
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1006/mthe.2000.0257