Fibroblast Matrix Gene Expression and Connective Tissue Remodeling: Role of Endothelin-1
Fibroblast Matrix Gene Expression and Connective Tissue Remodeling: Role of Endothelin-1
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Publisher
Danvers, MA: Elsevier Inc
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Language
English
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Publisher
Danvers, MA: Elsevier Inc
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Scope and Contents
Contents
This study examines endothelin-induced modulation of extracellular matrix synthesis and remodeling by fibroblasts, and its potential role in the pathogenesis of systemic sclerosis (scleroderma). Endothelin-1 promoted fibroblast synthesis of collagen types I and III, but not fibronectin, by a mechanism dependent upon both ETA and ETB receptors. Conv...
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Full title
Fibroblast Matrix Gene Expression and Connective Tissue Remodeling: Role of Endothelin-1
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Record Identifier
TN_cdi_proquest_miscellaneous_76982596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76982596
Other Identifiers
ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1046/j.1523-1747.2001.01256.x
