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Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_77235683

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

About this item

Full title

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 1995-05, Vol.375 (6526), p.61-64

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

AMYOTROPHIC lateral sclerosis (ALS) is a degenerative disease of motor neurons, characterized by depositions of neurofilaments in the perikarya and proximal axons. The pathogenesis of ALS remains poorly understood, but two lines of evidence suggest that neurofilament accumulation may play a causal role. First, transgenic mice that overexpress neuro...

Alternative Titles

Full title

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_77235683

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_77235683

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/375061a0

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