Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance
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Publisher
United States: The American Association for the Advancement of Science
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Language
English
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Publisher
United States: The American Association for the Advancement of Science
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Scope and Contents
Contents
Chloroquine-resistant Plasmodium falciparum accumulate significantly less chloroquine than susceptible parasites, and this is thought to be the basis of their resistance. However, the reason for the lower accumulation of chloroquine was unknown. The resistant parasite has now been found to release chloroquine 40 to 50 times more rapidly than the su...
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Full title
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance
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TN_cdi_proquest_miscellaneous_77839959
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_77839959
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.3317830
