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Major Histocompatibility Complex Class I–Restricted Infiltration and Destruction of Pancreatic Islet...

Major Histocompatibility Complex Class I–Restricted Infiltration and Destruction of Pancreatic Islet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78194474

Major Histocompatibility Complex Class I–Restricted Infiltration and Destruction of Pancreatic Islets by NOD Mouse-Derived β-Cell Cytotoxic CD8+ T-Cell Clones In Vivo

About this item

Full title

Major Histocompatibility Complex Class I–Restricted Infiltration and Destruction of Pancreatic Islets by NOD Mouse-Derived β-Cell Cytotoxic CD8+ T-Cell Clones In Vivo

Publisher

Alexandria, VA: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 1996-08, Vol.45 (8), p.1121-1131

Language

English

Formats

Publication information

Publisher

Alexandria, VA: American Diabetes Association

More information

Scope and Contents

Contents

NOD mouse-derived β-cell-specific cytotoxic T-cell (β-CTL) clones are diabetogenic in adult NOD mice, but only if co-injected with splenic CD4+ T-cells from diabetic animals. This investigation was initiated to determine whether infiltration of pancreatic islets by β-CTL is a major histocompatibility complex (MHC) class I-restricted response, and w...

Alternative Titles

Full title

Major Histocompatibility Complex Class I–Restricted Infiltration and Destruction of Pancreatic Islets by NOD Mouse-Derived β-Cell Cytotoxic CD8+ T-Cell Clones In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_78194474

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78194474

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/diab.45.8.1121

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