Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA
Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA
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Publisher
Washington, DC: The American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: The American Association for the Advancement of Science
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Contents
The human ferritin H chain messenger RNA contains a specific iron-responsive element (IRE) in its 5$^{\prime}$ untranslated region, which mediates regulation by iron of ferritin translation. An RNA gel retardation assay was used to demonstrate the affinity of a specific cytosolic binding protein for the IRE. A single-base deletion in the IRE elimin...
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Full title
Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA
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TN_cdi_proquest_miscellaneous_78394907
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78394907
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.3413484
