Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels...
Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight
About this item
Full title
Author / Creator
HARIHARAN, N , FARRELLY, D , HAGAN, D , HILLYER, D , ARBEENY, C , SABRAH, T , TRELOAR, A , BROWN, K , KALINOWSKI, S and MOOKHTIAR, K
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
Formats
Publication information
Publisher
Alexandria, VA: American Diabetes Association
Subjects
More information
Scope and Contents
Contents
Glucokinase is the predominant hexokinase in pancreatic beta-cells and liver parenchymal cells and functions as a critical component of the glucose-sensing apparatus in these glucose-responsive cell types. In the beta-cells, the sensing leads to insulin secretion, while the role in hepatocytes is thought to be in hepatic glucose uptake. To determin...
Alternative Titles
Full title
Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_78781698
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78781698
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/diab.46.1.11
