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Peptabody": A New Type of High Avidity Binding Protein

Peptabody": A New Type of High Avidity Binding Protein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78863847

Peptabody": A New Type of High Avidity Binding Protein

About this item

Full title

Peptabody": A New Type of High Avidity Binding Protein

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1997-03, Vol.94 (5), p.1663-1668

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A new type of high avidity binding molecule, termed ``peptabody'' was created by harnessing the effect of multivalent interaction. A short peptide ligand was fused via a semi-rigid hinge region with the coiled-coil assembly domain of the cartilage oligomeric matrix protein, resulting in a pentameric multivalent binding molecule. In the first peptab...

Alternative Titles

Full title

Peptabody": A New Type of High Avidity Binding Protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_78863847

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78863847

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.94.5.1663

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