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Inhibition of Diabetes by an Insulin-Reactive CD4 T-Cell Clone in the Nonobese Diabetic Mouse

Inhibition of Diabetes by an Insulin-Reactive CD4 T-Cell Clone in the Nonobese Diabetic Mouse

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79093804

Inhibition of Diabetes by an Insulin-Reactive CD4 T-Cell Clone in the Nonobese Diabetic Mouse

About this item

Full title

Inhibition of Diabetes by an Insulin-Reactive CD4 T-Cell Clone in the Nonobese Diabetic Mouse

Publisher

Alexandria, VA: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 1997-07, Vol.46 (7), p.1124-1132

Language

English

Formats

Publication information

Publisher

Alexandria, VA: American Diabetes Association

More information

Scope and Contents

Contents

A cloned Thl cell line was isolated from pancreatic lymph nodes of NOD mice that carries a T-cell receptor encoding Vβ14 and proliferates in response to NOD islets, islet supernatant, and crystalline bovine and rat insulin, specifically to a B-chain peptide bound to IAg7. The response to islet supernatant was reduced by 75% by anti-insulin antibody...

Alternative Titles

Full title

Inhibition of Diabetes by an Insulin-Reactive CD4 T-Cell Clone in the Nonobese Diabetic Mouse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_79093804

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79093804

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/diab.46.7.1124

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