Deactivation of Macrophages with Interleukin-4 Is the Key to the Isolation of Tropheryma whippelii
Deactivation of Macrophages with Interleukin-4 Is the Key to the Isolation of Tropheryma whippelii
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Publisher
Chicago, IL: The University of Chicago Press
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Language
English
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Publisher
Chicago, IL: The University of Chicago Press
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Contents
Whipple's disease is a systemic illness caused by a specific agent. Despite recognition of bacteria in lesions, efforts to isolate the causative agent remained futile. A novel strategy was devised to culture Whipple bacilli in deactivated mononuclear phagocytes. Infected tissue was inoculated into human phagocytes deactivated with interleukin (IL)-...
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Full title
Deactivation of Macrophages with Interleukin-4 Is the Key to the Isolation of Tropheryma whippelii
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TN_cdi_proquest_miscellaneous_79275200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79275200
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1086/514089
